Craig M Crews: search on Z-Library

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1

Targeted Protein Degradation by Small Molecules

Bondeson, Daniel P., Crews, Craig M.

Journal:

Annual Review of Pharmacology

Year:

2017

Language:

english

File:

PDF, 307 KB

english, 2017

2

Proteolysis–Targeting Chimeras: Harnessing the Ubiquitin–Proteasome System to Induce Degradation of Specific Target Proteins

Coleman, Kevin G., Crews, Craig M.

Journal:

Annual Review of Cancer Biology

Year:

2018

Language:

english

File:

PDF, 295 KB

english, 2018

3

Small-Molecule PROTACS: New Approaches to Protein Degradation

Toure, Momar, Crews, Craig M.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.34 MB

english, 2016

4

Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL

Lai, Ashton C., Toure, Momar, Hellerschmied, Doris, Salami, Jemilat, Jaime-Figueroa, Saul, Ko, Eunhwa, Hines, John, Crews, Craig M.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.33 MB

english, 2016

5

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase using PROTAC-mediated Degradation

Buhimschi, Alexandru D., Armstrong, Haley A, Toure, Momar, Jaime-Figueroa, Saul, Chen, Timothy L, Lehman, Amy M., Woyach, Jennifer A, Johnson, Amy J., Byrd, John C, Crews, Craig M

Journal:

Year:

2018

Language:

english

File:

PDF, 2.56 MB

english, 2018

6

Didemnin Binds to the Protein Palmitoyl Thioesterase Responsible for Infantile Neuronal Ceroid Lipofuscinosis

Craig M. Crews, William S. Lane and Stuart L. Schreiber

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 836 KB

english, 1996

7

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

Bondeson, Daniel P., Smith, Blake E., Burslem, George M., Buhimschi, Alexandru D., Hines, John, Jaime-Figueroa, Saul, Wang, Jing, Hamman, Brian D., Ishchenko, Alexey, Crews, Craig M.

Journal:

Cell Chemical Biology

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

8

Targeted protein degradation by PROTACs

Neklesa, Taavi K., Winkler, James D., Crews, Craig M.

Journal:

Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 409 KB

english, 2017

9

Addressing Kinase-Independent Functions of Fak via PROTAC-mediated Degradation

Cromm, Philipp M., Samarasinghe, Kusal, Hines, John, Crews, Craig M

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 964 KB

english, 2018

10

Remembering where we are: Positional information in salamander limb regeneration

Flowers, Grant Parker, Crews, Craig M

Journal:

Developmental Dynamics

Year:

2020

File:

PDF, 2.41 MB

2020

11

Targeted protein degradation: expanding the toolbox

Schapira, Matthieu, Calabrese, Matthew F., Bullock, Alex N., Crews, Craig M.

Journal:

Nature Reviews Drug Discovery

Year:

2019

File:

PDF, 2.87 MB

2019

12

The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase

Benjamin H.B. Kwok, Brian Koh, MacKevin I. Ndubuisi, Mikael Elofsson, Craig M. Crews

Journal:

Chemistry & Biology

Year:

2001

Language:

english

File:

PDF, 377 KB

english, 2001

13

再生能力の秘密を長文で読み解く

Flowers, G. Parker, Crews, Craig M.

Journal:

Year:

2018

File:

PDF, 972 KB

2018

14

Lineage tracing of genome-edited alleles reveals high fidelity axolotl limb regeneration

Flowers, Grant Parker, Sanor, Lucas D, Crews, Craig M

Journal:

Year:

2017

Language:

english

File:

PDF, 518 KB

english, 2017

15

Regeneration writ large

Flowers, G. Parker, Crews, Craig M.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

16

Scaffold hopping enables direct access to more potent PROTACs with in vivo activity

Burslem, George M, Bondeson, Daniel P, Crews, Craig M

Journal:

Chemical Communications

Year:

2020

File:

PDF, 1.10 MB

2020

17

The Anti-Angiogenic Agent Fumagillin Covalently Binds and Inhibits the Methionine Aminopeptidase, MetAP-2

Ny Sin, Lihao Meng, Margaret Q. W. Wang, James J. Wen, William G. Bornmann and Craig M. Crews

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 919 KB

english, 1997

18

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Cromm, Philipp M., Crews, Craig M.

Journal:

Cell Chemical Biology

Year:

2017

Language:

english

File:

PDF, 2.70 MB

english, 2017

19

Enhancing Anti-Proliferative Activity and Selectivity of a FLT-3 Inhibitor by PROTAC Conversion

Burslem, George M, Song, Jayoung, Chen, Xin, Hines, John, Crews, Craig M

Journal:

Journal of the American Chemical Society

Year:

2018

Language:

english

File:

PDF, 510 KB

english, 2018

20

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

Ashley R. Schneekloth, Mathieu Pucheault, Hyun Seop Tae, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 399 KB

english, 2008

21

Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure Degradation Relationships

Burslem, George M, Ottis, Philipp, Jaime-Figueroa, Saul, Morgan, Alicia, Cromm, Philipp, Toure, Momar, Crews, Craig

Journal:

Year:

2018

Language:

english

File:

PDF, 1.53 MB

english, 2018

22

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

Journal:

Chemistry & Biology

Year:

2015

Language:

english

File:

PDF, 1.84 MB

english, 2015

23

Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

Serebrenik, Yevgeniy V., Hellerschmied, Doris, Toure, Momar, López-Giráldez, Francesc, Brookner, Dennis, Crews, Craig M., Spang, Anne

Journal:

Molecular Biology of the Cell

Year:

2018

Language:

english

File:

PDF, 4.95 MB

english, 2018

24

Assessing Different E3 Ligases for Small Molecule-induced Protein Ubiquitination and Degradation

Ottis, Philipp, Toure, Momar, Cromm, Philipp M., Ko, Eunhwa, Gustafson, Jeffrey L., Crews, Craig M

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

25

A role for planar cell polarity signaling in angiogenesis

Pasquale Cirone, Shengda Lin, Hilary L. Griesbach, Yi Zhang, Diane C. Slusarski, Craig M. Crews

Journal:

Year:

2008

Language:

english

File:

PDF, 593 KB

english, 2008

26

Chemical Genetics: Adding to the Developmental Biology Toolbox

Jing-Ruey J Yeh, Craig M Crews

Journal:

Developmental Cell

Year:

2003

Language:

english

File:

PDF, 157 KB

english, 2003

27

Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z -Enamides. Some Preliminary Findings as to SAR

Lin, Songnian, Yang, Zhi-Qiang, Kwok, Benjamin H. B., Koldobskiy, Michael, Crews, Craig M., Danishefsky, Samuel J.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 211 KB

english, 2004

28

Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins

Neklesa, Taavi K, Tae, Hyun Seop, Schneekloth, Ashley R, Stulberg, Michael J, Corson, Timothy W, Sundberg, Thomas B, Raina, Kanak, Holley, Scott A, Crews, Craig M

Journal:

Nature Chemical Biology

Year:

2011

Language:

english

File:

PDF, 706 KB

english, 2011

29

Phorbol Ester Stimulates a Protein-Tyrosine/Threonine Kinase that Phosphorylates and Activates the Erk-1 Gene Product

A. Alessandrini, Craig M. Crews and R. L. Erikson

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.18 MB

english, 1992

30

Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy

Ottis, Philipp, Crews, Craig M.

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 4.06 MB

english, 2017

31

Temperature-dependent sex determination in the leopard gecko, Eublepharis macularius

Brian E. Viets, Alan Tousignant, Michael A. Ewert, Craig E. Nelson, David Crews

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1993

Language:

english

File:

PDF, 507 KB

english, 1993

32

Developing microcolin A analogs as biological probes

Amit K. Mandal, John Hines, Kouji Kuramochi, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 588 KB

english, 2005

33

Total Synthesis of (+)-7-Bromotrypargine and Unnatural Analogues: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance

Brogan, John T., Stoops, Sydney L., Crews, Brenda C., Marnett, Lawrence J., Lindsley, Craig W.

Journal:

ACS Chemical Neuroscience

Year:

2011

Language:

english

File:

PDF, 1.26 MB

english, 2011

34

Targeted protein destabilization reveals an estrogen-mediated ER stress response

Raina, Kanak, Noblin, Devin J, Serebrenik, Yevgeniy V, Adams, Alison, Zhao, Connie, Crews, Craig M

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 869 KB

english, 2014

35

Steuerung der intrazellulären Proteinmenge durch niedermolekulare Modulatoren des Ubiquitin-Proteasom-Systems

Buckley, Dennis L., Crews, Craig M.

Journal:

Angewandte Chemie

Year:

2014

Language:

german

File:

PDF, 2.20 MB

german, 2014

36

Targeted protein knockdown using small molecule degraders

Raina, Kanak, Crews, Craig M

Journal:

Current Opinion in Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

37

Retraction of âTargeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)â

Nalawansha, Dhanusha A., Paiva, Stacey-Lynn, Rafizadeh, Diane N., Pettersson, Mariell, Qin, Liena, Crews, Craig M.

Journal:

ACS Central Science

Year:

2020

File:

PDF, 337 KB

2020

38

Identification and Characterization of a Peptidic Ligand for Ras

Peter C. Gareiss, Ashley R. Schneekloth, Michael J. Salcius, Seung-Yong Seo, Craig M. Crews

Journal:

Year:

2010

Language:

english

File:

PDF, 319 KB

english, 2010

39

Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potency

Kyung Bo Kim, Jayhyuk Myung, Ny Sin, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 317 KB

english, 1999

40

Large-scale trapping features from the Great Basin, USA: The significance of leadership and communal gatherings in ancient foraging societies

Hockett, Bryan, Creger, Cliff, Smith, Beth, Young, Craig, Carter, James, Dillingham, Eric, Crews, Rachel, Pellegrini, Evan

Journal:

Quaternary International

Year:

2013

Language:

english

File:

PDF, 8.17 MB

english, 2013

41

Total Synthesis and Biological Evaluation of Tyroscherin

Tae, Hyun Seop, Hines, John, Schneekloth, Ashley R., Crews, Craig M.

Journal:

Organic Letters

Year:

2010

Language:

english

File:

PDF, 643 KB

english, 2010

42

Stereoselective Assembly of a 1,3-Diene via Coupling between an Allenic Acetate and a ( B )-Alkylborane: Synthetic Studies on Amphidinolide B1

Mandal, Amit K., Schneekloth,, John S., Crews, Craig M.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

43

Small-Molecule Modulation of Protein Homeostasis

Burslem, George M., Crews, Craig M.

Journal:

Chemical Reviews

Year:

2017

Language:

english

File:

PDF, 8.46 MB

english, 2017

44

Neurotrophic peptide aldehydes: Solid phase synthesis of fellutamide B and a simplified analog

John S. Schneekloth Jr., John L. Sanders, John Hines, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

45

Feeding the machine: mechanisms of proteasome-catalyzed degradation of ubiquitinated proteins

Journal:

Current Opinion in Chemical Biology

Year:

2003

Language:

english

File:

PDF, 729 KB

english, 2003

46

Towards subunit-specific proteasome inhibitors: synthesis and evaluation of peptide α', β'-epoxyketones

Mikael Elofsson, Ute Splittgerber, Jayhyuk Myung, Royce Mohan, Craig M Crews

Journal:

Chemistry & Biology

Year:

1999

Language:

english

File:

PDF, 150 KB

english, 1999

47

Disruption of Wnt Planar Cell Polarity Signaling by Aberrant Accumulation of the MetAP-2 Substrate Rab37

Thomas B. Sundberg, Nicole Darricarrere, Pasquale Cirone, Xia Li, Lucy McDonald, Xue Mei, Christopher J. Westlake, Diane C. Slusarski, Robert J. Beynon, Craig M. Crews

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

48

Chemical Genetics: Exploring the Role of the Proteasome in Cell Biology Using Natural Products and Other Small Molecule Proteasome Inhibitors

Kim, Kyung Bo, Crews, Craig M.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 106 KB

english, 2008

49

ChemInform Abstract: Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent.

Toure, Momar, Jaime-Figueroa, Saul, Burslem, George M., Crews, Craig M.

Journal:

Year:

2016

File:

PDF, 28 KB

2016

50

Small-molecule inhibitors of the cell cycle

Craig M Crews, Royce Mohan

Journal:

Current Opinion in Chemical Biology

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

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